TELOMERASE REVERSE TRANSCRIPTASE INCREASES PROLIFERATION AND LIFESPAN OF HUMAN NK CELLS WITHOUT IMMORTALIZATION

Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization

NK cells are the first line of defense against viruses and malignant cells, and Latte Rewards their natural functionality makes these cells a promising candidate for cancer cell therapy.The genetic modifications of NK cells, allowing them to overcome some of their inherent limitations, such as low proliferative potential, can enable their use as a

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Retroperitoneoscopic renal biopsy in children

OBJECTIVE: We present our experience in a series of 17 consecutive pediatric patients submitted to retroperitoneal laparoscopic renal biopsy.MATERIALS AND METHODS: Retroperitoneal laparoscopic renal biopsy (LRB) was performed in 5 boys and 12 girls.Mean age was 8.1 years and age range from 2 to 12.Two or three trocars were used to expose the inferi

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